adaptor proteins การใช้

• Enzymes and adaptor proteins are both responsive to various second messenger molecules.
• The SH3 proteins interact with adaptor proteins and tyrosine kinases.
• These adaptor proteins then couple to enzymes to amplify different cellular signals.
• This gene encodes a member of an adaptor protein family.
• Two examples of adaptor proteins are AP180 and epsin.
• It is an adaptor protein localized in the nucleus.
• In 2008 they discovered another adaptor protein, MITA, through expression cloning.
• It is located in the cytoplasm and is an adaptor protein involved in RAS.
• It is an inhibitory adaptor protein within Toll-like receptors ( TLR ).
• The Hop adaptor protein mediates the association of the molecular chaperones Hsp70 and Hsp90.
• An adaptor protein ( such as SOS ) recognizes the phosphorylated tyrosine on the receptor.
• Clathrin cannot bind to membrane or cargo directly and instead uses adaptor proteins to do this.
• Cullin 3 ubiquitinates Nrf2, while Keap1 is a substrate adaptor protein that facilitates the reaction.
• Initially, SH3 was described as a conserved sequence in the viral adaptor protein v-Crk.
• These adaptor proteins then recruit different factors including the effector protein kinase CHK2 and the tumor suppressor p53.
• FHL2 exerts its transcriptional regulatory effects by functioning as an adaptor protein interacting indirectly with the targeted genes.
• NCK belongs to family of adaptor proteins, There are two mammalian NCK genes, NCK1 and NCK2.
• A mouse ortholog, stem cell adaptor protein 1, shares 83 % identity with its human counterpart.
• Survival and PCD mechanisms are mediated through adaptor protein binding to the death domain of the p75NTR cytoplasmic tail.
• Actin polymerization is regulated by several adaptor proteins that can bind to the cytoplasmic motifs of the Robo receptors.